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Wesam Ismail

Ismail Wesam_PDVAHOR24
Predoctoral Fellowship in Value Assessment and Health Outcomes Research, 2024 University of Iowa

Risk of Infections with Induction Therapy Among Children with Kidney Transplant Using Real-World Data


Induction therapy is a group of drugs that help prevent the body from rejecting a new kidney after a transplant. In 2021, around 94% of children who had a kidney transplant used some form of this therapy. Different transplant centers choose different drugs for their patients as these drugs achieve the same goal. However, these drugs weaken the immune system making the patient more prone to infections. So far, we do not have enough information about how the use of these drugs affects the risk of infections in children with kidney transplant. In this study, we will investigate the risk of developing infections in children who did or did not use these drugs. We will use children’s data who got a kidney transplant between 2000 and 2019. This data will come from different transplant centers across the United States. Our goal is to learn how to make treatments better for children and improve their health outcomes.


I am so glad to receive the PhRMA Foundation Predoctoral Fellowship in Value Assessment-Health Outcomes Research. It emphasizes the importance of my research, which focuses on the safety of kidney transplant medications in children. This grant will be a great motivation for my future career as a researcher in health outcomes and pharmacoepidemiology.

Wesam Ismail