Nha Tran

Reducing Diabetes Overtreatment in Older Adults: A Patient-Centered Approach to Deprescribing
Summary
Overtreatment of diabetes in complex older adults is prevalent and can increase the risk of harmful side effects, falls, cognitive impairment, and hospitalization. Complex older adults with diabetes (COADs) are individuals with multiple chronic conditions, functional limitations, or cognitive impairment. Deprescribing, the process of reducing or stopping inappropriate medications, is key to addressing overtreatment. Successful deprescribing efforts depend on shared decision-making between patients and their clinicians. My research aims to understand what factors influence older adults when deciding whether to discuss deprescribing with clinicians. Using a nationally representative survey linked with claims data, I will examine how patient characteristics relate to willingness to deprescribe among COADs. I will also conduct a survey and interviews with overtreated COADs to explore what motivates or prevents them from initiating deprescribing conversations with clinicians. By leveraging real-world data, my research will identify patients more open to deprescribing and improve understanding of the barriers faced by those less likely to engage. My research will promote patient-centered conversations and reduce the risks associated with overtreatment in diabetes.
Watch a Q&A with Nha
Watch Tran’s presentation “Challenging the Prescribing Culture” at the University of Michigan’s 2025 Rackham King Talks.
It is a great honor to receive the PhRMA Foundation - Predoctoral Fellowship in Value Assessment and Health Outcomes Research award. This award not only recognizes my research efforts, but also emphasizes the significance of a patient-centered approach to deprescribing.