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Home > Self-Assessment Questions: Prescribing Drugs in Neonates, Infants, Children and Adolescents

Self-Assessment Questions: Prescribing Drugs in Neonates, Infants, Children and Adolescents

Question 1:
Starting in which year are drug manufacturers required to prove both effectiveness and safety of a drug to the FDA before marketing?

  1. 1938
  2. 1962
  3. 1966
  4. 1983

Question 2:
All drugs are tested in infants and children before approval.

True or False?

Question 3:
Body composition changes during development, and premature babies contain over 80% water.

True or False?

Question 4:
Glomerular filtration rate (GFR), a measure of the power of kidneys to clear medication, increases considerably in the first two weeks of life.

True or False?

Question 5:
Pharmacogenetic differences in drug metabolizing enzymes can affect how an individual baby responds to medications.

True or False?

Question 6:
The levels of drug-metabolizing enzymes change during development before and after birth.  The levels of some of these enzymes increase, some decrease, and others are not affected.

True or False?

Question 7:
A single dose of propofol, a sedative and anesthetic, in premature infants less than 10 days old can stay in the body for hours to days, much longer than in full-term infants.

True or False?

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